Bernardino Ghetti Selected Research

BU 224

10/2021

Astroglial tracer BU99008 detects multiple binding sites in Alzheimer's disease brain.

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Bernardino Ghetti Research Topics

Disease

75	Alzheimer Disease (Alzheimer's Disease) 10/2022 - 06/2002
32	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 07/2003
23	Frontotemporal Dementia (Semantic Dementia) 10/2022 - 11/2002
21	Prion Diseases (Transmissible Spongiform Encephalopathies) 01/2022 - 03/2003
19	Dementia (Dementias) 01/2021 - 06/2002
16	Tauopathies 01/2022 - 08/2002
14	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 10/2022 - 10/2007
13	Amyloid Plaque 01/2022 - 08/2005
11	Amyloidosis 01/2022 - 03/2003
10	Atrophy 01/2021 - 10/2007
10	Parkinson Disease (Parkinson's Disease) 01/2020 - 09/2005
8	Parkinsonian Disorders (Parkinsonism) 01/2016 - 08/2002
7	Disease Progression 04/2022 - 03/2010
7	Cognitive Dysfunction 12/2020 - 08/2012
6	Synucleinopathies 01/2022 - 01/2018
6	Sporadic Creutzfeldt-Jakob Disease 10/2021 - 11/2009
6	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 10/2021 - 03/2003
6	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2020 - 09/2005
6	Corticobasal Degeneration 01/2020 - 10/2007
5	Proteostasis Deficiencies 01/2021 - 03/2007
5	Multiple System Atrophy 01/2020 - 04/2006
5	Pick Disease of the Brain (Pick's Disease) 01/2020 - 03/2008
5	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 10/2019 - 11/2008
5	Neuroferritinopathy 01/2016 - 01/2008
5	Scrapie 06/2015 - 09/2005
4	Inflammation (Inflammations) 04/2022 - 07/2012
4	Nervous System Heredodegenerative Disorders 11/2020 - 08/2004
4	Chronic Traumatic Encephalopathy 01/2020 - 01/2019
3	TDP-43 Proteinopathies 01/2022 - 12/2014
3	Gliosis 10/2021 - 09/2006
3	Cerebral Cortical Thinning 01/2020 - 11/2013
3	Lewy Body Disease (Lewy Body Dementia) 01/2019 - 09/2005
3	Brain Diseases (Brain Disorder) 09/2011 - 02/2007
2	Death (Near-Death Experience) 11/2016 - 06/2016
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 10/2016 - 09/2009
2	Ataxia (Dyssynergia) 01/2016 - 07/2003
2	Movement Disorders (Movement Disorder) 01/2016 - 01/2008
2	Iron Overload 01/2016 - 01/2008
2	Down Syndrome (Down's Syndrome) 11/2014 - 12/2012
2	Hereditary Diffuse Leukoencephalopathy with Spheroids 08/2012 - 12/2011
2	Neuroinflammatory Diseases 01/2011 - 03/2010
1	Chronic Wasting Disease 11/2019

Drug/Important Bio-Agent (IBA)

44	Amyloid (Amyloid Fibrils)IBA 10/2022 - 03/2003
30	Proteins (Proteins, Gene)FDA Link 01/2021 - 06/2002
29	Prion ProteinsIBA 01/2022 - 03/2003
18	Biomarkers (Surrogate Marker)IBA 10/2022 - 08/2012
18	tau Proteins (tau Protein)IBA 10/2021 - 11/2002
14	PrionsIBA 11/2019 - 04/2005
10	Peptides (Polypeptides)IBA 01/2022 - 02/2004
9	DNA-Binding Proteins (DNA Binding Protein)IBA 10/2022 - 10/2007
9	Peptide Hydrolases (Proteases)FDA Link 10/2021 - 06/2002
9	Protein Isoforms (Isoforms)IBA 01/2021 - 11/2002
8	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 10/2021 - 01/2006
8	ProgranulinsIBA 01/2018 - 09/2006
7	SynucleinsIBA 01/2020 - 01/2018
7	Presenilin-1IBA 01/2018 - 08/2002
7	Apolipoproteins E (ApoE)IBA 09/2015 - 10/2007
7	PresenilinsIBA 01/2013 - 06/2002
6	IronIBA 11/2020 - 01/2008
6	Amyloid beta-PeptidesIBA 08/2015 - 06/2002
5	2- (4'- (methylamino)phenyl)- 6- hydroxybenzothiazole (Pittsburgh compound B)IBA 01/2022 - 11/2013
5	LigandsIBA 10/2021 - 01/2021
5	Codon (Codons)IBA 10/2021 - 11/2009
4	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 10/2005
4	ApoferritinsIBA 01/2016 - 01/2008
3	Methionine (L-Methionine)FDA Link 10/2021 - 11/2009
3	Valine (L-Valine)FDA Link 10/2021 - 11/2009
3	AntibodiesIBA 01/2020 - 02/2007
3	PrPSc ProteinsIBA 01/2017 - 07/2006
3	4- (N- methylamino)- 4'- (2- (2- (2- fluoroethoxy)ethoxy)ethoxy)stilbeneIBA 11/2016 - 08/2015
3	Ferritins (Ferritin)IBA 01/2016 - 01/2008
3	Flavin-Adenine Dinucleotide (FAD)IBA 01/2013 - 11/2008
3	alpha-SynucleinIBA 07/2010 - 09/2005
3	UbiquitinIBA 10/2007 - 08/2002
2	ThiophenesIBA 10/2021 - 01/2021
2	Nonsense Codon (Nonsense Mutation)IBA 01/2021 - 04/2011
2	Amyloidogenic ProteinsIBA 01/2021 - 10/2005
2	Tissue ExtractsIBA 01/2020 - 11/2019
2	Coloring Agents (Dyes)IBA 12/2019 - 11/2018
2	LipidsIBA 09/2019 - 01/2019
2	SilverIBA 01/2019 - 06/2016
2	Phosphotransferases (Kinase)IBA 01/2018 - 12/2014
2	Biological ProductsIBA 01/2018 - 01/2013
2	Indicators and Reagents (Reagents)IBA 09/2015 - 09/2006
2	Macrophage Colony-Stimulating FactorIBA 08/2012 - 12/2011
2	NeuroserpinIBA 09/2011 - 06/2002
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 03/2008 - 06/2002
2	Levodopa (L Dopa)FDA LinkGeneric 10/2007 - 09/2005
1	Serine (L-Serine)FDA Link 01/2022
1	Aspartic Acid (Aspartate)FDA Link 01/2022
1	Phenylalanine (L-Phenylalanine)FDA Link 01/2022
1	benzothiazoleIBA 10/2021
1	Metalloproteases (Metalloproteinases)IBA 10/2021
1	Selegiline (E250)FDA LinkGeneric 10/2021
1	2- (4,5- dihydro- 1H- imidazol- 2- yl)- 1- methyl- 1H- indoleIBA 10/2021
1	BU 224IBA 10/2021
1	thioflavin TIBA 01/2020
1	Single-Chain AntibodiesIBA 01/2020
1	Carrier Proteins (Binding Protein)IBA 01/2019

Therapy/Procedure

5	Therapeutics 01/2021 - 04/2005